KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAWR
All Species:
21.82
Human Site:
T221
Identified Species:
53.33
UniProt:
Q96IZ0
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96IZ0
NP_002574.2
340
36568
T221
L
L
Q
E
P
P
R
T
V
S
G
R
Y
K
S
Chimpanzee
Pan troglodytes
XP_509236
340
36611
T221
L
V
Q
E
P
P
R
T
V
S
G
R
Y
K
S
Rhesus Macaque
Macaca mulatta
XP_001085092
340
36573
T221
L
L
Q
E
P
P
R
T
V
S
G
R
Y
K
S
Dog
Lupus familis
XP_854250
423
47102
T305
L
L
Q
E
S
S
R
T
V
S
G
R
Y
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q925B0
333
35890
T214
L
P
Q
D
P
S
R
T
V
P
G
R
Y
K
S
Rat
Rattus norvegicus
Q62627
332
35847
T213
L
P
Q
D
P
S
R
T
V
P
G
R
Y
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506913
116
13365
K46
I
P
N
S
T
L
E
K
K
I
E
E
L
E
K
Chicken
Gallus gallus
XP_416112
284
31033
A176
R
Y
K
S
T
G
N
A
P
G
D
D
A
L
N
Frog
Xenopus laevis
NP_001087619
347
38029
T228
L
P
Q
E
T
V
K
T
A
G
S
N
R
Y
K
Zebra Danio
Brachydanio rerio
NP_001006015
305
33922
H217
S
D
E
E
G
S
R
H
R
H
R
H
G
R
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97.9
48.4
N.A.
78.2
76.7
N.A.
29.4
56.4
50.7
45.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
98.5
55.7
N.A.
84.1
82
N.A.
31.7
65.8
64.2
61.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
86.6
N.A.
73.3
73.3
N.A.
0
0
26.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
80
80
N.A.
13.3
13.3
33.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
10
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
20
0
0
0
0
0
0
10
10
0
0
10
% D
% Glu:
0
0
10
60
0
0
10
0
0
0
10
10
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
10
0
0
0
20
60
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
10
0
10
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
10
10
10
0
0
0
0
60
20
% K
% Leu:
70
30
0
0
0
10
0
0
0
0
0
0
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
10
0
0
0
0
10
0
0
10
% N
% Pro:
0
40
0
0
50
30
0
0
10
20
0
0
0
0
0
% P
% Gln:
0
0
70
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
0
0
70
0
10
0
10
60
10
10
0
% R
% Ser:
10
0
0
20
10
40
0
0
0
40
10
0
0
0
60
% S
% Thr:
0
0
0
0
30
0
0
70
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
0
10
0
0
60
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
60
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _